A bottle of Nature Span® Nattozimes 12000 FU Super Strength, white and pink label with text and branding.

Nattozimes® 12000FU Super Strength

$64.99

4.2

Quantity:

Bottle Size: 60 Veggie Capsules

60 Veggie Capsules

Key Benefits

✔ Supports healthy nutrient and oxygen delivery throughout the body
✔ Helps maintain normal enzyme activity and balanced protein metabolism
✔ Promotes flexibility and integrity of vascular tissues
✔ Complements a balanced lifestyle for overall circulatory wellness
✔ Provides a clean, vitamin K1-free daily formula

12000 FU Potency Nattozimes® Enzyme Vitamin K1-Free Produced in USA

The Nature Span® Difference

🛡️ Clinically Inspired Enzyme Potency

Each serving provides 12,000 Fibrinolytic Units (FU) from a precise blend of exo- and endo-proteases, delivering targeted enzyme activity that supports healthy circulation and overall metabolic balance.

🛡️ Soy-Free, Vitamin K-Free Innovation

Unlike traditional nattokinase, Nattozimes® is created through a proprietary non-soy fermentation process, making it suitable for those avoiding soy or vitamin K ingredients.

🛡️ Plant-Based, High-Purity Formula

This vegetarian enzyme complex is refined for high activity, purity, and consistency—providing a natural, eco-conscious approach to everyday vitality.

🛡️ Comprehensive Wellness Support

Beyond circulatory benefits, Nattozimes® enzymes help maintain efficient protein turnover and balanced metabolic function, supporting active lifestyles and long-term wellbeing.

Supplement Facts

Nature Span® Nattozimes® 12000 FU Super Strength

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Amount Per Serving

%DV

Exo/Endo Proteases

(as Nattozimes®)

(providing 12,000 Fibrinolytic Units [FU])

348 mg

†

† Daily Value not established.

Other Ingredients: Hypromellose (vegetable capsule), rice flour, and magnesium stearate. Gluten-Free / Soy-Free / Vegetarian

Nattozimes® is a registered trademark of Deerland Probiotics & Enzymes, Inc.

Usage & Safety

Who It’s For: Ideal for adults looking to support cardiovascular and cerebrovascular health, maintain healthy blood circulation, manage cholesterol levels, and promote vascular elasticity.*

Who Should Avoid It: Not recommended for pregnant or nursing women, or individuals with medical conditions or on medication without consulting a physician.*

Dosage: Take 1 capsule daily on an empty stomach.*

Bottle Supply: 60 vegetarian capsules (2-month supply).*

Best Before: 3 years from MFG date.*

Certified Quality: Manufactured in an FDA, UL and NSF-certified GMP facility, free from the eight major common allergens for purity and safety.*

Scientific References

Chen H, McGowan EM, Ren N, Lal S, Nassif N, Shad-Kaneez F, Qu X, Lin Y. Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomark Insights. 2018 Jul 5;13:1177271918785130. doi: 10.1177/1177271918785130.
Weng Y, Yao J, Sparks S, Wang KY. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. Int J Mol Sci. 2017 Feb 28;18(3):523. doi: 10.3390/ijms18030523.
Chen H, Chen J, Zhang F, Li Y, Wang R, Zheng Q, Zhang X, Zeng J, Xu F, Lin Y. Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants. Front Cardiovasc Med. 2022 Aug 22;9:964977. doi: 10.3389/fcvm.2022.964977. Erratum in: Front Cardiovasc Med. 2022 Dec 05;9:1076420. doi: 10.3389/fcvm.2022.1076420.
Cicero AFG, Fogacci F, Stoian AP, Toth PP. Red Yeast Rice for the Improvement of Lipid Profiles in Mild-to-Moderate Hypercholesterolemia: A Narrative Review. Nutrients. 2023 May 12;15(10):2288. doi: 10.3390/nu15102288.
Cicero AFG, Fogacci F, Banach M. Red Yeast Rice for Hypercholesterolemia. Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):192-199. doi: 10.14797/mdcj-15-3-192. PMID: 31687098; PMCID: PMC6822657.

Cardiovascular & Circulatory Support Nattozimes® 12000FU Super Strength

$64.99

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Premium Quality

Backed by science, crafted with patented ingredients. Read more about our standard.

Ultra-Potent Circulation Support

Nattozimes® is a high-quality enzyme blend that helps maintain natural enzymatic balance for circulatory comfort and overall wellness. Its superior bioavailability supports normal metabolic function and promotes everyday vitality naturally.

Nattozimes® 4th-Gen Enzyme

Standardized to 12,000 FU, this advanced multi-enzyme complex provides consistent enzyme activity. Food-grade fermentation ensures quality, stability, and dependable performance.

Enzyme Balance & Circulatory Support

Helps sustain normal fibrin turnover and balanced enzyme function, supporting smooth nutrient delivery and vascular comfort as part of daily wellness routines.

Vitamin K1-Free Assurance

Formulated without vitamin K1 or soy for broad dietary compatibility. Odor-free, clean, and designed for easy integration into your wellness regimen.

Red Yeast Rice Complement

Pairs nattokinase with red yeast rice to support healthy lipid metabolism. Together they offer well-rounded cardiovascular support alongside diet and exercise.

FAQ

What makes Nattozimes® 12000 FU “super strength”?

This formula delivers 12,000 FU (fibrinolytic units) per serving—providing concentrated enzyme support for maintaining natural metabolic balance and circulatory comfort.

How does Nattozimes® support overall wellness?

Nattozimes® helps maintain healthy enzyme activity that supports nutrient transport and natural fibrin turnover, contributing to smooth circulation and general vitality.

Is Nattozimes® the same as nattokinase?

Nattozimes® is a proprietary, plant-based enzyme blend designed to offer nattokinase-like support for circulatory wellness—without using soy or vitamin K.

Who can benefit from Nattozimes® 12000 FU?

Adults seeking additional support for circulatory comfort and metabolic balance may find it beneficial as part of a proactive wellness lifestyle. Individuals taking prescribed medication should consult a healthcare professional before use.

Excellent for vascular health

I’m in my late 50s and started this based on research around nattokinase for vascular support. My vascular function tests improved, and I feel steadier on walks. Very pleased overall.

Worth a try

I was skeptical at first. After two months, I feel a bit more “light” after long flights and less foot fatigue. Nothing dramatic but positive shifts.

Gentle but noticeable effects

At first I didn’t feel anything dramatic. But after maybe 3–4 weeks, I realized I wasn’t getting swollen ankles after a long day. That small change was meaningful.

Subtle but meaningful benefits

This is one of those supplements where you don’t feel fireworks, but over time things just get easier. Less stiffness, more comfort in circulation.

Works quietly, but works

This is not a “feel it in one day” type of product. It’s subtle: I notice less swelling, and mornings feel less stiff. For something so “quiet,” it’s doing more than I expected.