A box of NatureSpan® probiotic supplement with the text '30 Billion CFU 16-Strain Probiotic with FOS' displayed on the front.

The supplement facts of NatureSpan® probiotic supplement with the text '30 Billion CFU 16-Strain Probiotic with FOS' displayed on the front.

30 Billion CFU 16-Strain Probiotics

Q: Is 30 Billion CFU enough to make a difference?

Yes! In fact, it’s a sweet spot for daily digestive support. Too little won’t do much, too much can overwhelm sensitive tummies. 30 Billion CFU delivers a powerful boost of probiotics that’s effective and gentle enough for everyday use.

$59.99

Quantity:

Box Size: 30 Delayed-Release Veggie Capsules

30 Delayed-Release Veggie Capsules

Key Benefits

✔ Supports digestive comfort & regularity*
✔ Restores healthy microbiome after antibiotics*
✔ Supports lactose digestion & tolerance*
✔ Enhances immune defenses & gut barrier integrity*
✔ Promotes daily physical & mental well-being*

DuPont Strains 30 Billion CFU Delayed-Release Vegan Produced in USA

The NatureSpan® Difference

🛡️ DuPont Clinical Strains

Includes La-14™ and Lc-11™ with human data supporting digestive balance, immune function, and reliable survivability.

🛡️ 16-Strain, 30 Billion Spectrum

Balanced Lactobacillus and Bifidobacterium blend delivers broad coverage across the GI tract for diverse, resilient microbiota.

🛡️ Delayed-Release Vegan Capsules

Acid-resistant technology helps live cultures survive stomach acid for targeted intestinal delivery—no refrigeration required.

🛡️ Synbiotic & Shelf-Stable

FOS prebiotics nourish good bacteria; dual-foil blister sealing protects against heat, moisture, and oxygen to preserve potency.

Supplement Facts

NatureSpan® 30 Billion CFU 16-Strain Probiotics

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 30

Amount Per Serving

%DV

Probiotic Bacteria Blend

Total Cultures

274 mg30 Billion CFU

†

Lactobacillus acidophilus (La-14)

6.5 Billion CFU

†

Lactobacillus reuteri

1.5 Billion CFU

†

Lactobacillus helveticus

500 Million CFU

†

Lactobacillus rhamnosus (Lr-32)

3 Billion CFU

†

Lactococcus lactis

8 Billion CFU

†

Lactobacillus brevis

1.5 Billion CFU

†

Bifidobacterium bifidum

1 Billion CFU

†

Lactobacillus bulgaricus

325 Million CFU

†

Bifidobacterium lactis (Bl-04)

2.5 Billion CFU

†

Lactobacillus plantarum (Lp-115)

2 Billion CFU

†

Bifidobacterium longum (Bl-05)

500 Million CFU

†

Streptococcus thermophilus

1 Billion CFU

†

Bifidobacterium infantis

500 Million CFU

†

Lactobacillus salivarius (Ls-33)

500 Million CFU

†

Bifidobacterium breve (Bb-03)

500 Million CFU

†

Lactobacillus casei (Lc-11)

500 Million CFU

†

Fructooligosaccharide (FOS)

100 mg

†

† Daily Value not established.

Other Ingredients: Delayed-release vegetarian capsule (hypromellose, gellan gum), magnesium stearate, microcrystalline cellulose, inulin, and silicon dioxide (silica).

All strains are supplied by DuPont, a Fortune 500 company established in 1802.

Clinically researched strain La-14™.

Clinically researched strain Lc-11™.

Usage & Safety

Who It’s For: Ideal for adults seeking daily support for gut balance, relief from occasional constipation, diarrhea, or bloating, improved digestion (including lactose tolerance), enhanced immunity, and overall physical and mental wellness via the gut-brain axis.*

Who Should Avoid It: Not recommended for immunocompromised individuals, critically ill patients, or those taking medications without consulting a physician. Discontinue and seek medical advice if adverse reactions occur.*

Dosage: Take 1 capsule daily with a meal. Delayed-release vegetarian capsule; no refrigeration required.*

Bottle Supply: 30 capsules (1-month supply).*

Certified Quality: Manufactured in an FDA-registered, GMP and NSF-certified facility; free from the eight major allergens (milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy).*

Scientific References

Mohtashami M, Mohamadi M, Azimi-Nezhad M, Saeidi J, Nia FF, Ghasemi A. Lactobacillus bulgaricus and Lactobacillus plantarum improve diabetic wound healing through modulating inflammatory factors. Biotechnol Appl Biochem. 2021 Dec;68(6):1421-1431. doi: 10.1002/bab.2064. Epub 2020 Nov 17.
Huang C, Yue Q, Sun L, Di K, Yang D, Hao E, Wang D, Chen Y, Shi L, Zhou R, Zhao G, Chen H. Restorative effects of Lactobacillus rhamnosus LR-32 on the gut microbiota, barrier integrity, and 5-HT metabolism in reducing feather-pecking behavior in laying hens with antibiotic-induced dysbiosis. Front Microbiol. 2023 Apr 26;14:1173804. doi: 10.3389/fmicb.2023.1173804.
Chen S, Han P, Zhang Q, Liu P, Liu J, Zhao L, Guo L, Li J. Lactobacillus brevis alleviates the progress of hepatocellular carcinoma and type 2 diabetes in mice model via interplay of gut microflora, bile acid and NOTCH 1 signaling. Front Immunol. 2023 May 10;14:1179014. doi: 10.3389/fimmu.2023.1179014.
Neville BA, O'Toole PW. Probiotic properties of Lactobacillus salivarius and closely related Lactobacillus species. Future Microbiol. 2010 May;5(5):759-74. doi: 10.2217/fmb.10.35.
Li Y, Li Q, Yuan R, Wang Y, Guo C, Wang L. Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages. Theranostics. 2024 Apr 22;14(7):2719-2735. doi: 10.7150/thno.92350.

Gut Health & Digestive Support 30 Billion CFU 16-Strain Probiotics

$59.99

Fast Delivery for Your Family

We make sure wellness reaches your home without delay. Read more about our shipping policy

100% Satisfaction Guarantee

Shop with confidence, backed by our 30-day return policy.

Premium Quality

Backed by science, crafted with patented ingredients. Read more about our standard.

30 Billion CFU, 16-Strain Daily Gut Support

Clinically backed 16-strain probiotic with 30 Billion CFU to balance your microbiome, improve regularity, and support immunity. DuPont La-14™ & Lc-11™ in delayed-release vegan capsules with FOS; blister-sealed for potency—no refrigeration.

Clinically Researched DuPont Strains

Features La-14™ and Lc-11™ within a 16-strain complex. Human data support digestive balance, immune modulation, and consistent colonization for dependable results.

Broad-Spectrum, 30 Billion CFU

Targets upper and lower GI regions with complementary Lactobacillus and Bifidobacterium species. Promotes regularity, reduces gas and bloating, and strengthens microbial diversity.

Delayed-Release, High Survival

Vegetarian, acid-resistant capsules help cultures pass through the stomach and release in the intestines, maximizing viability where benefits matter most.

Synbiotic Power & Stability

FOS prebiotics feed beneficial bacteria for a thriving microbiome. Dual-foil blister packaging shields from heat, moisture, and oxygen for potency—no fridge required.

FAQ

Why 16 strains instead of just a few?

Because your gut is like a rainforest: the more variety, the healthier the ecosystem. Our 16 carefully chosen strains cover a wide range of digestive and immune support functions, so you’re not just feeding one type of good bacteria, you’re supporting a whole thriving community.

Is 30 Billion CFU enough to make a difference?

Yes! In fact, it’s a sweet spot for daily digestive support. Too little won’t do much, too much can overwhelm sensitive tummies. 30 Billion CFU delivers a powerful boost of probiotics that’s effective and gentle enough for everyday use.

Can kids or seniors take this probiotic?

This formula is designed for adults, but seniors often find it especially helpful for digestion and immune balance. For kids, it’s best to check with a healthcare professional first since their needs are a little different.

What’s the best time of day to take it?

Morning, night, or with lunch — it’s flexible!

Many people like to take it with their first meal of the day so they can stay consistent. The most important thing is taking it daily, so find a time that fits your routine and stick with it.

30 Billion CFU 16-Strain Probiotics

Key Benefits

The NatureSpan® Difference

We make sure wellness reaches your home without delay. Read more about our shipping policy

Shop with confidence, backed by our 30-day return policy.

Backed by science, crafted with patented ingredients. Read more about our standard.

FAQ

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